Microbiomes More in Flux in Patients with Inflammatory Bowel Disease

Patients with inflammatory bowel disease are more likely to see dramatic shifts in the make-up of the community of microbes in their gut than healthy people, according to the results of a study published online Feb. 13 in Nature Microbiology.

While scientists have known that there are differences in the bacteria and other microbes that make up the gut microbiome in IBD patients, this is one of the largest studies to watch the microbiome over a period of time. The findings indicate that the biggest difference in the microbiome of patients is the way it fluctuates -- what the researchers call "volatile dysbiosis."



The results help physicians and scientists understand the disease more fully and potentially offer new ways to track the disease and monitor patients.

The findings come from a team of scientists from Sweden, Spain, Germany and the United States. Janet Jansson of the Department of Energy's Pacific Northwest National Laboratory is the corresponding author of the paper. Read more here.


Related Content: Strategies in Inflammatory Bowel Disease Management: Integrating Evidence and Collaborative Care