Smoking Elevates Risk Factors in Rheumatoid Arthritis

New findings reveal an association between smoking and the concurrent presence of multiple rheumatoid arthritis (RA)-related autoantibodies, rather than only anti-citrullinated protein antibodies (ACPA).



In a study published in Arthritis Research & Therapy, investigators sought to determine whether association of smoking with RA was limited only to anti-citrullinated protein antibodies (ACPA), or there was an association with several other autoantibodies.

The investigators examined the association of smoking with rheumatoid factor (RF) and anti-CCP2 in a population-based cohort of health individuals; the association of smoking and anti-cyclic citrullinated peptide antibodies (anti-CCP2), IgM-RF, and anti-carbamylated protein antibodies (anti-CarP); and whether smoking was associated with the breadth of the autoimmune response. Read more here. 


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